English Name: 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine
CAS Number: 3680-69-1
Molecular Formula: C₆H₄ClN₃
Molecular Weight: 153.57
EINECS Number: 628-079-2
Overview: 4-Chloropyrido-pyrimidine is an important pharmaceutical intermediate. It is used as an intermediate for the raw material drug tofacitinib, which is used for treating adult patients with moderate to severe rheumatoid arthritis who have insufficient or intolerant responses to methotrexate. 4-Chloropyrido-pyrimidine is also an important raw material for developing many antibacterial, anti-tumor, and anti-spindle worm drugs.
Applications: 4-Chloropyrido-pyrimidine is a white to off-white powder, used as an intermediate for the raw material drug tofacitinib, which is used for treating adult patients with moderate to severe rheumatoid arthritis who have insufficient or intolerant responses to methotrexate; tofacitinib intermediate.